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HSF1A

A small molecule human HSF1 (heat shock transcription factor 1) activator; activates HSF1 in mammalian and fly cells, elevates protein chaperone expression, ameliorates protein misfolding and cell death in polyQ-expressing neuronal precursor cells and protects against cytotoxicity in a fly model of polyQ-mediated neurodegeneration; also interacts with components of the TRiC/CCT complex.

Product Specifications

CAS Number

1196723-93-9

Product Name Alternative

HSF1 activator

Purity

>98% (HPLC)

Solubility

DMSO: ≥150 mg/mL (< 1 mg/ml refers to the product slightly soluble or insoluble)

Smiles

O=S (C1=CC=C (CC) C=C1) (NC2=CC (C3=CC=CS3) =NN2C4=CC=CC=C4) =O

Molecular Formula

C21H19N3O2S2

Molecular Weight

409.522

Storage Conditions

Storage temperature: -20°C. Stability: ≥ 2 years

Notes

For research use only.

Other Product Names

4-ethyl-N- (1-phenyl-3- (thiophen-2-yl) -1H-pyrazol-5-yl) benzenesulfonamide

Available Sizes

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