Ixazomib Citrate
MLN9708 immediately hydrolyzed to MLN2238, the biologically active form, on exposure to aqueous solutions or plasma. MLN2238 inhibits the chymotrypsin-like proteolytic (β5) site of the 20S proteasome with IC50/Ki of 3.4 nM/0.93 nM, less potent to β1 and little activity to β2. Phase 3.
Product Specifications
CAS Number
1201902-80-8
Product Name Alternative
Ixazomib Citrate
Field of Research
Pharmacology & Drug Discovery
Purity
>98% (HPLC)
Solubility
DMSO: 100 mg/mL (193.37 mM)
Smiles
B1 (OC (=O) CC (O1) (CC (=O) O) C (=O) O) [C@H] (CC (C) C) NC (=O) CNC (=O) C2=C (C=CC (=C2) Cl) Cl
Molecular Formula
C20H23BCl2N2O9
Molecular Weight
517.12
Storage Conditions
Storage temperature: -20°C. Stability: ≥ 2 years
Notes
For research use only.
Available Sizes
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