GDF-8 Polyclonal Antibody
Product Specifications
Background
Growth/differentiation factor 8 (Mstn, GDF-8) is a member of the bone morphogenetic protein (BMP) family and the TGF-beta superfamily. This group of proteins is characterized by a polybasic proteolytic processing site which is cleaved to produce a mature protein containing seven conserved cysteine residues. It is expressed specifically in developing and adult skeletal muscle. It exists as a homodimer, and interacts with WFIKKN2, leading to inhibit its activity. This protein can act specifically as a negative regulator of skeletal muscle growth. It regulates cell growth and differentiation in both embryonic and adult tissues.
Abbreviation
GDF-8
UniProt
O14793
Host
Rabbit
Reactivity
Human; Mouse; Rat
Immunogen
Recombinant Human GDF-8 Protein expressed by E.coli
Target
Growth/differentiation factor 8; GDF-8; Myostatin; MSTN; GDF8
Clonality
Polyclonal
Conjugation
Unconjugated
Applications
WB
Field of Research
Cancer; Signal Transduction
Purification
Antigen Affinity Purification
Concentration
1 mg/mL
Dilution
WB 1:500-1:1000
Buffer
PBS with 0.02% sodium azide,1% protective protein and 50% glycerol, pH7.4
Shipping Conditions
The product is shipped with ice pack, upon receipt, store it immediately at the temperature recommended.
Storage Conditions
Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.
Calculated Molecular Weight
43kDa
Observed Molecular Weight
35kDa-43kDa
Isotype
IgG
Available Sizes
Documents
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