WZ4003
WZ4003 is a highly specific NUAK kinase inhibitor with IC50 of 20 nM and 100 nM for NUAK1 and NUAK2, respectively, without significant inhibition on 139 other kinases.
Product Specifications
CAS Number
1214265-58-3
Product Name Alternative
WZ4003 | WZ-4003 | WZ 4003
Purity
>98% (HPLC)
Solubility
DMSO:7 mg/mL (14.08 mM) ; Ethanol:<1 mg/mL (<1 mM) ; Water:<1 mg/mL (<1 mM)
Smiles
CCC (NC1=CC=CC (OC2=NC (NC3=CC=C (N4CCN (C) CC4) C=C3OC) =NC=C2Cl) =C1) =O
Molecular Formula
C25H29ClN6O3
Molecular Weight
496.99
Storage Conditions
Storage temperature: -20°C. Stability: ≥ 2 years
Notes
For research use only.
Other Product Names
N-[3-[[5-chloro-2-[[2-methoxy-4- (4-methyl-1-piperazinyl) phenyl]amino]-4-pyrimidinyl]oxy]phenyl]-propanamide
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