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GSK4112

A potent and selective small molecule Rev-erbα agonist with EC50 of 0.4 uM in biochemical assay; mediates the repression of Rev-erbα target gene bmal1 in liver cells, and inhibits and shifts the phase of gluconeogenesis in primary mouse hepatocytes.

Product Specifications

CAS Number

1216744-19-2

Product Name Alternative

SR6452 | GSK-4112 | GSK 4112 | SR-6452 | SR 6452

Purity

>98% (HPLC)

Solubility

10 mM in DMSO

Smiles

O=C (OC (C) (C) C) CN (CC1=CC=C (Cl) C=C1) CC2=CC=C ([N+] ([O-]) =O) S2

Molecular Formula

C18H21ClN2O4S

Molecular Weight

396.8883

Storage Conditions

Storage temperature: -20°C. Stability: ≥ 2 years

Notes

For research use only.

Other Product Names

Glycine, N-[ (4-chlorophenyl) methyl]-N-[ (5-nitro-2-thienyl) methyl]-, 1,1-dimethylethyl ester

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