GSK4112
A potent and selective small molecule Rev-erbα agonist with EC50 of 0.4 uM in biochemical assay; mediates the repression of Rev-erbα target gene bmal1 in liver cells, and inhibits and shifts the phase of gluconeogenesis in primary mouse hepatocytes.
Product Specifications
CAS Number
1216744-19-2
Product Name Alternative
SR6452 | GSK-4112 | GSK 4112 | SR-6452 | SR 6452
Purity
>98% (HPLC)
Solubility
10 mM in DMSO
Smiles
O=C (OC (C) (C) C) CN (CC1=CC=C (Cl) C=C1) CC2=CC=C ([N+] ([O-]) =O) S2
Molecular Formula
C18H21ClN2O4S
Molecular Weight
396.8883
Storage Conditions
Storage temperature: -20°C. Stability: ≥ 2 years
Notes
For research use only.
Other Product Names
Glycine, N-[ (4-chlorophenyl) methyl]-N-[ (5-nitro-2-thienyl) methyl]-, 1,1-dimethylethyl ester
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