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WZB117

WZB117 (WZB-117) is a small-molecule inhibitor of glucose transporter 1 (GLUT1), inhibits glucose transport and cancer cell proliferation with IC50 of 10 uM; decreases in levels of Glut1 protein, intracellular ATP, and glycolytic enzymes in treated cancer cells, inhibits cancer growth in tumor-bearing nude mice; also inhibits the self-renewal and tumor-initiating capacity of cancer stem cells (CSCs) .

Product Specifications

CAS Number

1223397-11-2

Product Name Alternative

WZB-117

Purity

>98% (HPLC)

Solubility

DMSO: 36.8 mg/mL (100 mM) ; Ethanol: 36.8 mg/mL (100 mM) (< 1 mg/ml refers to the product slightly soluble or insoluble)

Smiles

FC1=C (OC (C2=CC=CC (O) =C2) =O) C (OC (C3=CC=CC (O) =C3) =O) =CC=C1

Molecular Formula

C20H13FO6

Molecular Weight

368.316

Storage Conditions

Storage temperature: -20°C. Stability: ≥ 2 years

Notes

For research use only.

Other Product Names

3-Fluoro-1,2-phenylene bis (3-hydroxybenzoate)

Available Sizes

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