WZB117
WZB117 (WZB-117) is a small-molecule inhibitor of glucose transporter 1 (GLUT1), inhibits glucose transport and cancer cell proliferation with IC50 of 10 uM; decreases in levels of Glut1 protein, intracellular ATP, and glycolytic enzymes in treated cancer cells, inhibits cancer growth in tumor-bearing nude mice; also inhibits the self-renewal and tumor-initiating capacity of cancer stem cells (CSCs) .
Product Specifications
CAS Number
1223397-11-2
Product Name Alternative
WZB-117
Purity
>98% (HPLC)
Solubility
DMSO: 36.8 mg/mL (100 mM) ; Ethanol: 36.8 mg/mL (100 mM) (< 1 mg/ml refers to the product slightly soluble or insoluble)
Smiles
FC1=C (OC (C2=CC=CC (O) =C2) =O) C (OC (C3=CC=CC (O) =C3) =O) =CC=C1
Molecular Formula
C20H13FO6
Molecular Weight
368.316
Storage Conditions
Storage temperature: -20°C. Stability: ≥ 2 years
Notes
For research use only.
Other Product Names
3-Fluoro-1,2-phenylene bis (3-hydroxybenzoate)
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