HA-130
A potent and selective inhibitor of autotaxin with IC50 of 28 nM; shows no effect on chymotryptic, caspase, and tryptic activities of the proteasome, alkaline phosphatase and a broad-spectrum PEDs (IC50>10 uM) ; inhibits ATX-driven melanoma cell migration and decreases circulating LPA levels in mice.
Product Specifications
CAS Number
1229652-21-4
Product Name Alternative
HA130 | HA 130
Purity
>98% (HPLC)
Solubility
DMSO: ≥ 39 mg/mL
Smiles
OB (C1=CC=CC (COC2=CC=C (/C=C (SC (N3CC4=CC=C (F) C=C4) =O) /C3=O) C=C2) =C1) O
Molecular Formula
C24H19BFNO5S
Molecular Weight
463.2858
Storage Conditions
Storage temperature: -20°C. Stability: ≥ 2 years
Notes
For research use only.
Other Product Names
Boronic acid, B-[3-[[4-[[3-[ (4-fluorophenyl) methyl]-2,4-dioxo-5-thiazolidinylidene]methyl]phenoxy]methyl]phenyl]-
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