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HA-130

A potent and selective inhibitor of autotaxin with IC50 of 28 nM; shows no effect on chymotryptic, caspase, and tryptic activities of the proteasome, alkaline phosphatase and a broad-spectrum PEDs (IC50>10 uM) ; inhibits ATX-driven melanoma cell migration and decreases circulating LPA levels in mice.

Product Specifications

CAS Number

1229652-21-4

Product Name Alternative

HA130 | HA 130

Purity

>98% (HPLC)

Solubility

DMSO: ≥ 39 mg/mL

Smiles

OB (C1=CC=CC (COC2=CC=C (/C=C (SC (N3CC4=CC=C (F) C=C4) =O) /C3=O) C=C2) =C1) O

Molecular Formula

C24H19BFNO5S

Molecular Weight

463.2858

Storage Conditions

Storage temperature: -20°C. Stability: ≥ 2 years

Notes

For research use only.

Other Product Names

Boronic acid, B-[3-[[4-[[3-[ (4-fluorophenyl) methyl]-2,4-dioxo-5-thiazolidinylidene]methyl]phenoxy]methyl]phenyl]-

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