CDK4-IN-1
CDK4 inhibitor is a novel and specific CDK4/Cyclin D1 inhibitor with an IC50 of 10 nM; 1500 and 500 fold than CDK1/Cyclin B (IC50>15 uM) and CDK2/Cyclin A (IC50=5.265 uM) respectively.
Product Specifications
CAS Number
1256963-02-6
Product Name Alternative
LEE011 analog | CDK4-IN-1 | CDK4IN-1 | CDK4-IN1
Field of Research
Signal Transduction
Purity
>98% (HPLC)
Solubility
DMSO: 10 mM
Smiles
CN (C1CCN (C2=CN=C (NC3=NC=CC (C4=C (C (C) C) NN=C4Cl) =N3) C=C2) CC1) C
Molecular Formula
C22H29ClN8
Molecular Weight
440.97
Storage Conditions
Storage temperature: -20°C. Stability: ≥ 2 years
Notes
For research use only.
Other Product Names
4- (3-Chloro-5-propan-2-yl-1H-pyrazol-4-yl) -N-[5-[4- (dimethylamino) piperidin-1-yl]pyridin-2-yl]pyrimidin-2-amine
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