BMS-687453
A potent and selective PPARα agonist with EC50 of 10 nM for human PPARα and 410-fold selectivity over human PPARγ in PPAR-GAL4 transactivation assays; has negligible cross-reactivity against a panel of human nuclear hormone receptors including PPARδ; demonstrates an excellent pharmacological and safety profile for the treatment of atherosclerosis and dyslipidemia.Dyslipidemia Preclinical
Product Specifications
CAS Number
1000998-59-3
Product Name Alternative
BMS687453 | BMS 687453
Purity
>98% (HPLC)
Solubility
DMSO: ≥ 31 mg/mL
Smiles
O=C (O) CN (CC1=CC=CC (OCC2=C (C) OC (C3=CC=C (Cl) C=C3) =N2) =C1) C (OC) =O
Molecular Formula
C22H21ClN2O6
Molecular Weight
444.8649
Storage Conditions
Storage temperature: -20°C. Stability: ≥ 2 years
Notes
For research use only.
Other Product Names
Glycine, N-[[3-[[2- (4-chlorophenyl) -5-methyl-4-oxazolyl]methoxy]phenyl]methyl]-N- (methoxycarbonyl) -
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