What is the catalog number for Daclatasvir dihydrochloride?

The catalog number for Daclatasvir dihydrochloride is orb1227165.

What sizes are available for Daclatasvir dihydrochloride?

Daclatasvir dihydrochloride is available in the following size(s): 200 mg, 500 mg, 1 g, 5 mg, 10 mg, 25 mg, 50 mg, 100 mg.

How many pack sizes does Daclatasvir dihydrochloride come in?

Daclatasvir dihydrochloride is available in 8 different pack sizes.

Is Daclatasvir dihydrochloride in stock?

Daclatasvir dihydrochloride is currently made to order / not held in immediate stock. Contact us for lead time.

Daclatasvir dihydrochloride

A potent HCV NS5A inhibitor with EC50 of <50 pM against genotype 1 replicons; exhibits picomolar EC (50) towards replicons expressing a broad range of HCV genotypes and the JFH-1 genotype 2a infectious virus in cell culture.HCV Infection Approved (In Vitro) :Daclatasvir (BMS-790052) demonstrates potent inhibitory activity towards all genotypes tested, with EC50 values ranging from 9 pM to 146 pM. Daclatasvir inhibits HCV replicon genotype 1a, 1b, 2a, 3a, 4a and 5a with EC50 values of 50 pM, 9 pM, 71 pM, 146 pM, 12 pM and 33 pM, respectively. Daclatasvir is a potent inhibitor of the JFH-1 genotype 2a infectious virus that replicates in cell culture (EC50=28 pM) . Daclatasvir (BMS-790052) binds tightly to NS5A33-202 and NS5A26-202 with Kds of 8 nM and 210 nM, respectively. (In Vivo) :Daclatasvir (BMS-790052; 30 mg/kg; oral administration; daily; for 27 days) treatment reduces serum HCV RNA titers very rapidly by ~1.5 log10 at day 3.

Product Specifications

CAS Number

1009119-65-6

Product Name Alternative

BMS-790052 dihydrochloride | BMS790052 dihydrochloride | BMS 790052 dihydrochloride

Field of Research

Pharmacology & Drug Discovery

Purity

>98% (HPLC)

Solubility

DMSO: ≥ 56 mg/mL

Smiles

CC (C) [C@@H] (C (=O) N1CCC[C@H]1C2=NC=C (N2) C3=CC=C (C=C3) C4=CC=C (C=C4) C5=CN=C (N5) [C@@H]6CCCN6C (=O) [C@H] (C (C) C) NC (=O) OC) NC (=O) OC.Cl.Cl

Molecular Formula

C40H52Cl2N8O6

Molecular Weight

811.7969

Storage Conditions

Storage temperature: -20°C. Stability: ≥ 2 years

Notes

For research use only.

Other Product Names

Carbamic acid, N, N'-[[1,1'-biphenyl]-4,4'-diylbis[1H-imidazole-5,2-diyl- (2S) -2,1-pyrrolidinediyl[ (1S) -1- (1-methylethyl) -2-oxo-2,1-ethanediyl]]]bis-, C, C'-dimethyl ester, hydrochloride (1:2)