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Valbenazine

A novel, highly selective vesicular monoamine transporter 2 (VMAT2) inhibitor; is approved for the treatment of tardive dyskinesia.Other Indication Phase 3 Clinical (In Vitro) :Valbenazine exhibits VMAT2 binding affinity in rat striatum and human platelets with Kis of 110 and 150 nM, respectively. (In Vivo) :Valbenazine (10 mg/kg; orally) induces ptosis (primarily an adrenergic response) and increases plasma prolactin primarily a dopaminergic response.

Product Specifications

CAS Number

1025504-45-3

Product Name Alternative

NBI-98854

Field of Research

Pharmacology & Drug Discovery

Purity

>98% (HPLC)

Solubility

10 mM in DMSO

Smiles

CC (C) CC1CN2CCC3=CC (=C (C=C3C2CC1OC (=O) C (C (C) C) N) OC) OC

Molecular Formula

C24H38N2O4

Molecular Weight

418.5695

Storage Conditions

Storage temperature: -20°C. Stability: ≥ 2 years

Notes

For research use only.

Other Product Names

L-Valine, (2R,3R,11bR) -1,3,4,6,7,11b-hexahydro-9,10-dimethoxy-3- (2-methylpropyl) -2H-benzo[a]quinolizin-2-yl ester

Available Sizes

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