Levetiracetam
Levetiracetam (UCB L059) is a novel anticonvulsant with antihyperalgesic efficacy in inflammatory pain. (In Vitro) :Levetiracetam increases the transcription of HDACs and recruits corepressor complex on O6-Methylguanine-DNA-methyltransferase (MGMT) promoter, thus silencing its activity.Levetiracetam sensitizes (40 μg/mL) glioblastoma multiforme stem-like cells (GSCs) to Temozolomide (250 μM) treatment.MGMT expression is downregulated in GCSCs treated with Levetiracetam (40 μg/mL) (In Vivo) :Levetiracetam (10, 25, or 50 mg/kg) suppresses behavioral and electrographic seizure activity during neonatal hypoxia.
Product Specifications
CAS Number
102767-28-2
Product Name Alternative
UCB L059
Field of Research
Pharmacology & Drug Discovery
Purity
>98% (HPLC)
Solubility
Ethanol: 34 mg/mL (199.75 mM) ; Water: 34 mg/mL (199.75 mM) ; DMSO: 34 mg/mL (199.75 mM)
Smiles
O=C (N) [C@H] (CC) N1C (CCC1) =O
Molecular Formula
C8H14N2O2
Molecular Weight
170.21
Storage Conditions
Storage temperature: -20°C. Stability: ≥ 2 years
Notes
For research use only.
Other Product Names
(S) -2- (2-oxopyrrolidin-1-yl) butanamide
Available Sizes
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