Levamlodipine
Amlodipine is a synthetic dihydropyridine and a calcium channel blocker with antihypertensive and antianginal properties. Amlodipine inhibits the influx of extracellular calcium ions into myocardial and peripheral vascular smooth muscle cells, thereby preventing vascular and myocardial contraction. This results in a dilatation of the main coronary and systemic arteries, decreased myocardial contractility, increased blood flow and oxygen delivery to the myocardial tissue, and decreased total peripheral resistance. This agent may also modulate multi-drug response (MDR) activity through inhibition of the p-glycoprotein efflux pump.
Product Specifications
CAS Number
103129-82-4
Product Name Alternative
Levamlodipine | S-Amlodipine |
Field of Research
Pharmacology & Drug Discovery
Purity
>98% (HPLC)
Solubility
DMSO: 10 mM
Smiles
O=C (C1=C (COCCN) NC (C) =C (C (OC) =O) [C@@H]1C2=CC=CC=C2Cl) OCC
Molecular Formula
C20H25N2O5Cl
Molecular Weight
408.88
Storage Conditions
Storage temperature: -20°C. Stability: ≥ 2 years
Notes
For research use only.
Other Product Names
3-ethyl 5-methyl (S) -2- ((2-aminoethoxy) methyl) -4- (2-chlorophenyl) -6-methyl-1,4-dihydropyridine-3,5-dicarboxylate
Available Sizes
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