Tamsulosin hydrochloride
Tamsulosin is a selective antagonist at alpha-1A and alpha-1B-adrenoceptors in the prostate, prostatic capsule, prostatic urethra, and bladder neck. At least three discrete alpha1-adrenoceptor subtypes have been identified: alpha-1A, alpha-1B and alpha-1D; their distribution differs between human organs and tissue. Approximately 70% of the alpha1-receptors in human prostate are of the alpha-1A subtype. Blockage of these receptors causes relaxation of smooth muscles in the bladder neck and prostate.
Product Specifications
CAS Number
106463-17-6
Product Name Alternative
LY253351 | YM-12617-1
Field of Research
Pharmacology & Drug Discovery
Purity
>98% (HPLC)
Solubility
Water: 215.9 mg/L
Smiles
O=S (C1=CC=C (C[C@H] (NCCOC2=CC=CC=C2OCC) C) C=C1) (N) =O.[H]Cl
Molecular Formula
C20H29ClN2O5S
Molecular Weight
444.97
Storage Conditions
Storage temperature: -20°C. Stability: ≥ 2 years
Notes
For research use only.
Other Product Names
5-[ (2R) -2-[[2- (2-Ethoxyphenoxy) ethyl]amino]propyl]-2-benzenesulfonamide hydrochloride
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