CY-09
CY-09 (NLRP3 inhibitor CY-09) is a selective and direct NLRP3 inhibitor, binds to the ATP-binding motif of NLRP3 NACHT domain and inhibits NLRP3 ATPase activity; suppresses NLRP3 inflammasome assembly and activation, shows remarkable therapeutic effects on mouse models of cryopyrin-associated autoinflammatory syndrome (CAPS) and type 2 diabetes.
Product Specifications
CAS Number
1073612-91-5
Product Name Alternative
NLRP3 inhibitor CY-09
Purity
>98% (HPLC)
Solubility
DMSO: 77 mg/mL (181.8 mM) (< 1 mg/ml refers to the product slightly soluble or insoluble)
Smiles
O=C (O) C1=CC=C (/C=C (SC (N2CC3=CC=CC (C (F) (F) F) =C3) =S) \C2=O) C=C1
Molecular Formula
C19H12F3NO3S2
Molecular Weight
423.424
Storage Conditions
Storage temperature: -20°C. Stability: ≥ 2 years
Notes
For research use only.
Other Product Names
Benzoic acid, 4-[[4-oxo-2-thioxo-3-[[3- (trifluoromethyl) phenyl]methyl]-5-thiazolidinylidene]methyl]-
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