Balofloxacin
Balofloxacin is a quinolone antibiotic, inhibiting the synthesis of bacterial DNA by interference with the enqyme DNA gyrase. (In Vitro) :Balofloxacin (25 mg/mL; 1 h) decreases the growth of S. aureus that adhered to human corneal epithelial cells (HCECs) .Balofloxacin inhibits the S. aureus ATCC 25923, with a MIC of 0.125 mg/mL.Balofloxacin (0.05-500 μg/mL; 72 h) does not induce toxicity on the HCECs at a low concentration, such as 0.625 mg/mL. (In Vivo) :Balofloxacin (200 mg/kg/day; p.o. for 5 d) reduces the counts of viable M. pneumonia in the lungs of hamsters.Balofloxacin eye drops (0.5%) is effective in S. aureus bacterial keratitis of rabbits.
Product Specifications
CAS Number
127294-70-6
Product Name Alternative
Q-35
Field of Research
Pharmacology & Drug Discovery
Purity
>98% (HPLC)
Solubility
DMSO: 5 mg/mL (12.83 mM)
Smiles
CNC1CCCN (C1) c2c (cc3c (c2OC) n (cc (c3=O) C (=O) O) C4CC4) F
Molecular Formula
C20H24FN3O4
Molecular Weight
389.42
Storage Conditions
Storage temperature: -20°C. Stability: ≥ 2 years
Notes
For research use only.
Other Product Names
(+-) -1-Cyclopropyl-6-fluoro-1,4-dihydro-8-methoxy-7- (3- (methylamino) piperidino) -4-oxo-3-quinolinecarboxylic acid
Available Sizes
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