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RO-8994

A highly potent and selective, small-molecule p53-MDM2 inhibitor with HRFT IC50 of 5 nM; shows marked improvement in both in vitro and in vivo pharmacological properties.

Product Specifications

CAS Number

1309684-94-3

Product Name Alternative

RO8994

Purity

>98% (HPLC)

Solubility

DMSO: ≥ 45 mg/mL

Smiles

CC (C) (C) CC1C2 (C (C (N1) C (=O) NC3=C (C=C (C=C3) C (=O) N) OC) C4=C (C (=CC=C4) Cl) F) C5=C (C=C (C=C5) Cl) NC2=O

Molecular Formula

C31H31Cl2FN4O4

Molecular Weight

613.5067

Storage Conditions

Storage temperature: -20°C. Stability: ≥ 2 years

Notes

For research use only.

Other Product Names

Spiro[3H-indole-3,3'-pyrrolidine]-5'-carboxamide, N-[4- (aminocarbonyl) -2-methoxyphenyl]-6-chloro-4'- (3-chloro-2-fluorophenyl) -2'- (2,2-dimethylpropyl) -1,2-dihydro-2-oxo-, (2'S,3R,4'S,5'R) -

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