RO-8994
A highly potent and selective, small-molecule p53-MDM2 inhibitor with HRFT IC50 of 5 nM; shows marked improvement in both in vitro and in vivo pharmacological properties.
Product Specifications
CAS Number
1309684-94-3
Product Name Alternative
RO8994
Purity
>98% (HPLC)
Solubility
DMSO: ≥ 45 mg/mL
Smiles
CC (C) (C) CC1C2 (C (C (N1) C (=O) NC3=C (C=C (C=C3) C (=O) N) OC) C4=C (C (=CC=C4) Cl) F) C5=C (C=C (C=C5) Cl) NC2=O
Molecular Formula
C31H31Cl2FN4O4
Molecular Weight
613.5067
Storage Conditions
Storage temperature: -20°C. Stability: ≥ 2 years
Notes
For research use only.
Other Product Names
Spiro[3H-indole-3,3'-pyrrolidine]-5'-carboxamide, N-[4- (aminocarbonyl) -2-methoxyphenyl]-6-chloro-4'- (3-chloro-2-fluorophenyl) -2'- (2,2-dimethylpropyl) -1,2-dihydro-2-oxo-, (2'S,3R,4'S,5'R) -
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