Diphenylpyraline hydrochloride
Diphenylpyraline Hcl is a first-generation antihistamine with anticholinergic effects, acts as a dopamine reuptake inhibitor, shows to be useful in the treatment of Parkinsonism. (In Vitro) :Diphenylpyraline hydrochloride (10 μM) markedly inhibits dopamine uptakein mouse nucleus accumbens slices. (In Vivo) :Diphenylpyraline hydrochloride (intraperitoneal injection; 5-10 mg/kg) elevates extracellular dopamine levels (~200%) in mouse nucleus accumbens and induces locomotor activation in mice.
Product Specifications
CAS Number
132-18-3
Product Name Alternative
Diphenylpyraline hydrochloride | Diafen hydrochloride | Diaphen
Field of Research
Pharmacology & Drug Discovery
Purity
>98% (HPLC)
Solubility
Soluble in DMSO
Smiles
CN1CCC (OC (C2=CC=CC=C2) C3=CC=CC=C3) CC1.[H]Cl
Molecular Formula
C19H23NO·HCl
Molecular Weight
317.85
Storage Conditions
Storage temperature: -20°C. Stability: ≥ 2 years
Notes
For research use only.
Other Product Names
Piperidine, 4- (diphenylmethoxy) -1-methyl-, hydrochloride
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