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YL0919

An orally active, dual 5-HT1A agonist and selective serotonin reuptake inhibitor with Ki of 0.19 nM and IC50 of 1.78 nM, respectively; shows no affinity for dopamine receptors and others 5-HT receptors; inhibits forskolin-stimulated cAMP formation and 5-HT uptake in both rat cortical synaptosomes and recombinant cells; significantly reverses the depressive-like behaviors in chronically stressed rats.

Product Specifications

CAS Number

1339058-04-6

Product Name Alternative

YL-0919 | YL 0919

Purity

>98% (HPLC)

Solubility

DMSO: ≥ 30 mg/mL

Smiles

O=C1C=CC=CN1CC2 (O) CCN (CC3=CC=CC=C3) CC2.[H]Cl

Molecular Formula

C18H23ClN2O2

Molecular Weight

334.8404

Storage Conditions

Storage temperature: -20°C. Stability: ≥ 2 years

Notes

For research use only.

Other Product Names

2 (1H) -Pyridinone, 1-[[4-hydroxy-1- (phenylmethyl) -4-piperidinyl]methyl]-, hydrochloride (1:1)

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