YL0919
An orally active, dual 5-HT1A agonist and selective serotonin reuptake inhibitor with Ki of 0.19 nM and IC50 of 1.78 nM, respectively; shows no affinity for dopamine receptors and others 5-HT receptors; inhibits forskolin-stimulated cAMP formation and 5-HT uptake in both rat cortical synaptosomes and recombinant cells; significantly reverses the depressive-like behaviors in chronically stressed rats.
Product Specifications
CAS Number
1339058-04-6
Product Name Alternative
YL-0919 | YL 0919
Purity
>98% (HPLC)
Solubility
DMSO: ≥ 30 mg/mL
Smiles
O=C1C=CC=CN1CC2 (O) CCN (CC3=CC=CC=C3) CC2.[H]Cl
Molecular Formula
C18H23ClN2O2
Molecular Weight
334.8404
Storage Conditions
Storage temperature: -20°C. Stability: ≥ 2 years
Notes
For research use only.
Other Product Names
2 (1H) -Pyridinone, 1-[[4-hydroxy-1- (phenylmethyl) -4-piperidinyl]methyl]-, hydrochloride (1:1)
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