XMD16-5
XMD16-5 is a potent Ack1 (TNK2) inhibitor with IC50 of 0.38 uM in ELISA assay; exhibits potent inhibition of growth of the TNK2 mutant expressing cell lines with IC50s of 16 nM and 77 nM for the D163E and R806Q mutations.
Product Specifications
CAS Number
1345098-78-3
Product Name Alternative
XMD16-5 | XMD-16-5 | XMD 16-5 | XMD165
Purity
>98% (HPLC)
Solubility
DMSO: ≥ 29 mg/mL
Smiles
OC (CC1) CCN1C (C=C2) =CC=C2NC3=NC=C4C (N (C) C (C=CC=C5) =C5C (N4) =O) =N3
Molecular Formula
C23H24N6O2
Molecular Weight
416.47566
Storage Conditions
Storage temperature: -20°C. Stability: ≥ 2 years
Notes
For research use only.
Other Product Names
6H-Pyrimido[4,5-b][1,4]benzodiazepin-6-one, 5,11-dihydro-2-[[4- (4-hydroxy-1-piperidinyl) phenyl]amino]-11-methyl-
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