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ML-240

ML240 is a potent, selective and reversible AAA ATPase p97 inhibitor (IC50=100 nM) ; blocks degradation of p97-dependent proteasome substrate with an IC50 of 0.9 uM; induces caspases 3 and 7 and potently blocked proliferation in HCT15 and SW403 cells.

Product Specifications

CAS Number

1346527-98-7

Product Name Alternative

ML 240 | ML-240

Purity

>98% (HPLC)

Solubility

DMSO: 16.5 mg/mL

Smiles

COC1=CC=CC2=C (NCC3=CC=CC=C3) N=C (N4C5=CC=CC=C5N=C4N) N=C12

Molecular Formula

C23H20N6O

Molecular Weight

396.4445

Storage Conditions

Storage temperature: -20°C. Stability: ≥ 2 years

Notes

For research use only.

Other Product Names

4-Quinazolinamine, 2- (2-amino-1H-benzimidazol-1-yl) -8-methoxy-N- (phenylmethyl) -

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