ML-240
ML240 is a potent, selective and reversible AAA ATPase p97 inhibitor (IC50=100 nM) ; blocks degradation of p97-dependent proteasome substrate with an IC50 of 0.9 uM; induces caspases 3 and 7 and potently blocked proliferation in HCT15 and SW403 cells.
Product Specifications
CAS Number
1346527-98-7
Product Name Alternative
ML 240 | ML-240
Purity
>98% (HPLC)
Solubility
DMSO: 16.5 mg/mL
Smiles
COC1=CC=CC2=C (NCC3=CC=CC=C3) N=C (N4C5=CC=CC=C5N=C4N) N=C12
Molecular Formula
C23H20N6O
Molecular Weight
396.4445
Storage Conditions
Storage temperature: -20°C. Stability: ≥ 2 years
Notes
For research use only.
Other Product Names
4-Quinazolinamine, 2- (2-amino-1H-benzimidazol-1-yl) -8-methoxy-N- (phenylmethyl) -
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