PI3K-IN-1
PI3K-IN-1 is a potent inhibitor of PI3K, extracted from patent WO2012103524 A2 and WO2013147649 A2. (In Vitro) :PI3K-IN-1 (25 μM) blocks PI3K/Akt signaling pathways. By using the PI3K inhibitor PI3K-IN-1, TGF-β1 induced transformation into myofibroblast is also inhibited, with relatively reduced expressions of α-SMA, Col-1 and Timp-1.
Product Specifications
CAS Number
1349796-36-6
Product Name Alternative
SAR245409 | Voxtalisib
Field of Research
Signal Transduction
Purity
>98% (HPLC)
Solubility
DMSO: 27.5 mg/mL
Smiles
O=C (NC1=CC=C (S (=O) (NC2=NC3=CC=CC=C3N=C2NC4=CC (OC) =CC (OC) =C4) =O) C=C1) C5=CC=C (C) C (OC) =C5
Molecular Formula
C31H29N5O6S
Molecular Weight
599.6569
Storage Conditions
Storage temperature: -20°C. Stability: ≥ 2 years
Notes
For research use only.
Other Product Names
N- (4- (N- (3- ((3,5-dimethoxyphenyl) amino) quinoxalin-2-yl) sulfamoyl) phenyl) -3-methoxy-4-methylbenzamide
Available Sizes
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