Pibrentasvir
Pibrentasvir (ABT-530) is a novel and pan-genotypic HCV NS5A inhibitor with EC50 of 1.4-5.0 pM against HCV replicons containing NS5A genotypes 1-6; demonstrates potent antiviral activity and acceptable safety during 3-day monotherapy in patients with HCV genotype 1 infection, with or without compensated cirrhosis.HCV Infection Phase 2 Clinical.
Product Specifications
CAS Number
1353900-92-1
Product Name Alternative
ABT-530
Field of Research
Pharmacology & Drug Discovery
Purity
>98% (HPLC)
Solubility
DMSO: 60 mg/mL, need ultrasonic (< 1 mg/ml refers to the product slightly soluble or insoluble)
Smiles
FC1=CC=C (C2CCN (C3=C (F) C=C (N4[C@@H] (C5=C (F) C=C6C (N=C ([C@H]7N (C ([C@@H] (NC (OC) =O) [C@H] (OC) C) =O) CCC7) N6) =C5) CC[C@@H]4C8=C (F) C=C9C (N=C ([C@H]%10N (C ([C@@H] (NC (OC) =O) [C@H] (OC) C) =O) CCC%10) N9) =C8) C=C3F) CC2) C=C1
Molecular Formula
C57H65F5N10O8
Molecular Weight
1113.2
Storage Conditions
Storage temperature: -20°C. Stability: ≥ 2 years
Notes
For research use only.
Other Product Names
Dimethyl ((2S,2'S,3R,3'R) - ((2S,2'S) - (((2R,5R) -1- (3,5-difluoro-4- (4- (4-fluorophenyl) piperidin-1-yl) phenyl) pyrrolidine-2,5-diyl) bis (6-fluoro-1H-benzo[d]imidazole-5,2-diyl) ) bis (pyrrolidine-2,1-diyl) ) bis (3-methoxy-1-oxobutane-1,2-diyl) ) dicarbamate
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