Palonosetron hydrochloride
Palonosetron (INN, trade name Aloxi) is a 5-HT3 antagonist used in the prevention and treatment of chemotherapy-induced nausea and vomiting (CINV) . It is the most effective of the 5-HT3 antagonists in controlling delayed CINV nausea and vomiting that appear more than 24 hours after the first dose of a course of chemotherapy and is the only drug of its class approved for this use by the U.S. Food and Drug Administration. As of 2008, it is the most recent 5-HT3 antagonist to enter clinical use.
Product Specifications
CAS Number
135729-62-3
Product Name Alternative
Aloxi | RS 25259-197
Field of Research
Pharmacology & Drug Discovery
Purity
>98% (HPLC)
Solubility
Water: 67 mg/mL (201.27 mM)
Smiles
C1C[C@@H]2CN (C (=O) C3=C2C (=CC=C3) C1) [C@@H]4CN5CCC4CC5.Cl
Molecular Formula
C19H24N2O·HCl
Molecular Weight
332.87
Storage Conditions
Storage temperature: -20°C. Stability: ≥ 2 years
Notes
For research use only.
Available Sizes
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