PP121
A multitargeted, dual tyrosine and PI3K kinase inhibitor of PDGFR, Hck, mTOR, VEGFR2, Src and Abl with IC50 of 2, 8, 10, 12, 14 and 18 nM; also inhibits Ret, VEGFR-2, 110α/mTOR, potently inhibits both tyrosine kinases and PI3Ks but not serine-threonine kinases.
Product Specifications
CAS Number
1092788-83-4
Product Name Alternative
PP 121 | PP-121
Purity
>98% (HPLC)
Solubility
10 mM in DMSO
Smiles
NC1=C2C (N (C3CCCC3) N=C2C4=CN=C (NC=C5) C5=C4) =NC=N1
Molecular Formula
C17H17N7
Molecular Weight
319.3638
Storage Conditions
Storage temperature: -20°C. Stability: ≥ 2 years
Notes
For research use only.
Other Product Names
1H-Pyrazolo[3,4-d]pyrimidin-4-amine, 1-cyclopentyl-3- (1H-pyrrolo[2,3-b]pyridin-5-yl) -
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