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PP121

A multitargeted, dual tyrosine and PI3K kinase inhibitor of PDGFR, Hck, mTOR, VEGFR2, Src and Abl with IC50 of 2, 8, 10, 12, 14 and 18 nM; also inhibits Ret, VEGFR-2, 110α/mTOR, potently inhibits both tyrosine kinases and PI3Ks but not serine-threonine kinases.

Product Specifications

CAS Number

1092788-83-4

Product Name Alternative

PP 121 | PP-121

Purity

>98% (HPLC)

Solubility

10 mM in DMSO

Smiles

NC1=C2C (N (C3CCCC3) N=C2C4=CN=C (NC=C5) C5=C4) =NC=N1

Molecular Formula

C17H17N7

Molecular Weight

319.3638

Storage Conditions

Storage temperature: -20°C. Stability: ≥ 2 years

Notes

For research use only.

Other Product Names

1H-Pyrazolo[3,4-d]pyrimidin-4-amine, 1-cyclopentyl-3- (1H-pyrrolo[2,3-b]pyridin-5-yl) -

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