BRAF inhibitor 13
A potent and selective B-Raf inhibitor with IC50 of 0.31 uM and 2 nM for A375 proliferation and A375 p-ERK respectively; induces proliferation and hyperplasia in normal tissues of mice.
Product Specifications
CAS Number
1093100-40-3
Product Name Alternative
BRAF-IN-13
Field of Research
Pharmacology & Drug Discovery
Purity
>98% (HPLC)
Solubility
DMSO: ≥53 mg/mL (< 1 mg/ml refers to the product slightly soluble or insoluble)
Smiles
CC1=C (C2=C (C=C1) C (=NC=C2) NC3=CC=C (C=C3) Cl) NC4=C (C=CC=N4) C5=C6C (=NC=N5) N=CN6
Molecular Formula
C26H19ClN8
Molecular Weight
478.944
Storage Conditions
Storage temperature: -20°C. Stability: ≥ 2 years
Notes
For research use only.
Other Product Names
N5- (3- (9H-purin-6-yl) pyridin-2-yl) -N1- (4-chlorophenyl) -6-methylisoquinoline-1,5-diamine
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