CCT 137690
A potent, orally bioavailable Aurora kinases inhibitor with IC50 of 15/25/19 nM for Aurora A/B/C; displays antiproliferative activity in a range of human tumor cell lines, including SW620 colon carcinoma (GI50=0.30 uM) and A2780 ovarian cancer cell line (GI50=0.14 uM) ; exhibits in vivo efficacy with no observed toxicities in SW620 colon carcinoma xenografts.
Product Specifications
CAS Number
1095382-05-0
Product Name Alternative
CCT-137690 | CCT137690
Purity
>98% (HPLC)
Solubility
10 mM in DMSO
Smiles
CN1CCN (C2=CC=C (C3=NC4=C (N5CCN (CC6=NOC (C) =C6) CC5) C (Br) =CN=C4N3) C=C2) CC1
Molecular Formula
C26H31BrN8O
Molecular Weight
551.4813
Storage Conditions
Storage temperature: -20°C. Stability: ≥ 2 years
Notes
For research use only.
Other Product Names
3H-Imidazo[4,5-b]pyridine, 6-bromo-7-[4-[ (5-methyl-3-isoxazolyl) methyl]-1-piperazinyl]-2-[4- (4-methyl-1-piperazinyl) phenyl]-
Available Sizes
Frequently Asked Questions
Explore Other Products
Browse additional items from our catalog
Mouse CXCL12 Recombinant Protein Tag Free Lyophilized
Mouse CXCL12 Recombinant Protein Tag Free Lyophilized
CDKN2B, CT (CDKN2B, MTS2, Cyclin-dependent kinase 4 inhibitor B, Multiple tumor suppressor 2, p14-INK4b, p15-INK4b) (MaxLight 405) discontinued
![4-[ (Tributylstannyl) methoxy]-1-butanol](https://cdn.genprice.uk/genprice/uk/genprice2.webp)