MG-101
A potent inhibitor of cysteine proteases including calpain I (Ki= 190 nM), calpain II (Ki= 220 nM), cathepsin B (Ki= 150 nM) and cathepsin L (Ki= 500 pM) ; activates p53-dependent apoptosis in tumor cell lines; increases activated p53, p21 and caspase levels and promotes cell cycle arrest through inhibition of cyclin D degradation in vitro.
Product Specifications
CAS Number
110044-82-1
Product Name Alternative
Calpain inhibitor I | ALLN
Purity
>98% (HPLC)
Solubility
10 mM in DMSO
Smiles
CC (C) C[C@H] (NC (C) =O) C (N[C@@H] (CC (C) C) C (N[C@H] (CCCC) C=O) =O) =O
Molecular Formula
C20H37N3O4
Molecular Weight
383.5255
Storage Conditions
Storage temperature: -20°C. Stability: ≥ 2 years
Notes
For research use only.
Other Product Names
L-Leucinamide, N-acetyl-L-leucyl-N-[ (1S) -1-formylpentyl]-
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