IM-12
IM-12 is a novel potent GSK-3β inhibitor with IC50 of 53 nM, significantly increases the β-catenin level and activates canonical Wnt signalling; attenuates cell proliferation of ReNcell VM cells, induces nuclear accumulation of beta-catenin.
Product Specifications
CAS Number
1129669-05-1
Product Name Alternative
IM 12 | IM12
Purity
>98% (HPLC)
Solubility
DMSO: ≥ 54.9 mg/mL
Smiles
FC (C=C1) =CC=C1CCNC (C2=O) =C (C (N2C) =O) C (C3=C (C=CC=C3) N4) =C4C
Molecular Formula
C22H20FN3O2
Molecular Weight
377.4115
Storage Conditions
Storage temperature: -20°C. Stability: ≥ 2 years
Notes
For research use only.
Other Product Names
1H-Pyrrole-2,5-dione, 3-[[2- (4-fluorophenyl) ethyl]amino]-1-methyl-4- (2-methyl-1H-indol-3-yl) -
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