Cidofovir
The prodrug of cidofovir diphosphate that inhibits cytomegalovirus (CMV) viral replication by selectively inhibiting viral DNA polymerases; also incorporates itself into viral DNA hence inhibiting viral DNA synthesis during reproduction.CMV Infection Approved (In Vitro) :Cidofovir (5-100 μM, 72 hours) has antiviral activity against feline herpesvirus type-1 (FHV-1) with an IC50 of 11 μM, and can reduce Crandell-Reese feline kidney cell counts in a dose-dependent manner.Cidofovir (10-1000 μM, 24-120 hours) can reduce cancer cell viability and induces apoptosis. (In Vivo) :Cidofovir (subcutaneous injection, 100 mg/kg, 3-6 days interval, 21 days) is highly protective against death from cowpox virus (CPV) infection at high doses in female weanling BALB/c mice.
Product Specifications
CAS Number
113852-37-2
Product Name Alternative
GS-0504 | HPMPC | (S) -HPMPC
Field of Research
Pharmacology & Drug Discovery
Purity
>98% (HPLC)
Solubility
H2O: 6.4 mg/mL (Need warming)
Smiles
OC[C@@H] (OCP (O) (O) =O) CN1C=CC (N) =NC1=O
Molecular Formula
C8H14N3O6P
Molecular Weight
279.187
Storage Conditions
Storage temperature: -20°C. Stability: ≥ 2 years
Notes
For research use only.
Other Product Names
Phosphonic acid, P-[[ (1S) -2- (4-amino-2-oxo-1 (2H) -pyrimidinyl) -1- (hydroxymethyl) ethoxy]methyl]-
Available Sizes
Frequently Asked Questions
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