BMS-794833
BMS794833 is a potent ATP competitive inhibitor of Met/VEGFR2 with IC50 of 1.7 nM/15 nM; also inhibits Ron, Axl and Flt-3 with IC50200 RTKs, non-RTKs and serine/threonine kinases; inhibits the cell growth in GTL-16 gastric carcinomas with an IC50 of 39 nM; active in multiple tumor models.Solid Tumors Phase 1 Clinical.
Product Specifications
CAS Number
1174046-72-0
Product Name Alternative
BMS794833
Purity
>98% (HPLC)
Solubility
10 mM in DMSO
Smiles
C1=CC (=CC=C1C2=CNC=C (C2=O) C (=O) NC3=CC (=C (C=C3) OC4=C (C (=NC=C4) N) Cl) F) F
Molecular Formula
C23H15ClF2N4O3
Molecular Weight
468.84
Storage Conditions
Storage temperature: -20°C. Stability: ≥ 2 years
Notes
For research use only.
Other Product Names
3-Pyridinecarboxamide, N-[4-[ (2-amino-3-chloro-4-pyridinyl) oxy]-3-fluorophenyl]-5- (4-fluorophenyl) -1,4-dihydro-4-oxo-
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