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NSC 23766 trihydrochloride

A specific small molecule inhibitor of Rac GTPase; potently blockes serum or PDGF-induced Rac1 activation and lamellipodia formation without affecting the activity of endogenous Cdc42 or RhoA; inhibits the proliferation, anchorage-independent growth and invasion phenotypes of human prostate cancer PC-3 cells.

Product Specifications

CAS Number

1177865-17-6

Product Name Alternative

NSC-23766 trihydrochloride | NSC23766 trihydrochloride

Field of Research

Neuroscience

Purity

>98% (HPLC)

Solubility

H2O: ≥ 32 mg/mL; DMSO: 7.6 mg/mL

Smiles

Cl.Cl.Cl.CCN (CC) CCCC (C) NC1=NC (C) =CC (NC2=CC3=C (N) C=C (C) N=C3C=C2) =N1 |c:14,20,26,29,31, t:11,18,23|

Molecular Formula

C24H38Cl3N7

Molecular Weight

530.9644

Storage Conditions

Storage temperature: -20°C. Stability: ≥ 2 years

Notes

For research use only.

Other Product Names

4,6-Quinolinediamine, N6-[2-[[4- (diethylamino) -1-methylbutyl]amino]-6-methyl-4-pyrimidinyl]-2-methyl-, trihydrochloride

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