NSC 23766 trihydrochloride
A specific small molecule inhibitor of Rac GTPase; potently blockes serum or PDGF-induced Rac1 activation and lamellipodia formation without affecting the activity of endogenous Cdc42 or RhoA; inhibits the proliferation, anchorage-independent growth and invasion phenotypes of human prostate cancer PC-3 cells.
Product Specifications
CAS Number
1177865-17-6
Product Name Alternative
NSC-23766 trihydrochloride | NSC23766 trihydrochloride
Field of Research
Neuroscience
Purity
>98% (HPLC)
Solubility
H2O: ≥ 32 mg/mL; DMSO: 7.6 mg/mL
Smiles
Cl.Cl.Cl.CCN (CC) CCCC (C) NC1=NC (C) =CC (NC2=CC3=C (N) C=C (C) N=C3C=C2) =N1 |c:14,20,26,29,31, t:11,18,23|
Molecular Formula
C24H38Cl3N7
Molecular Weight
530.9644
Storage Conditions
Storage temperature: -20°C. Stability: ≥ 2 years
Notes
For research use only.
Other Product Names
4,6-Quinolinediamine, N6-[2-[[4- (diethylamino) -1-methylbutyl]amino]-6-methyl-4-pyrimidinyl]-2-methyl-, trihydrochloride
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