Rebeprazole sodium
Rebeprazole sodium is a proton pump inhibitor. (In Vitro) :Rabeprazole attenuates the cell viability of the human gastric cancer cells following treatment with 0.2 mM for 16 hours.Rabeprazole completely inhibits the phosphorylation of ERK1/2 in the MKN-28 cells. The gastric cancer cell line MKN-28 is cultured in acidic culture media (pH 5.4) for 2 hours. Pretreatment with Rabeprazole (0.2 mM for 2 hours) leads to strong inhibition of ERK 1/2 phosphorylation in the MKN-28 cells. (In Vivo) :Rabeprazole (10 mg/kg; P.O.; every 48 h for 18 weeks) course leads to a significant decline in bone mineral density (BMD) and decreases serum calcium level and produces secondary hyperparathyroidism in female mice.
Product Specifications
CAS Number
117976-90-6
Product Name Alternative
E 3810 | LY307640
Purity
>98% (HPLC)
Solubility
DMSO: 76mg/ml (199.26 mM) ; Water: 76mg/ml (199.26 mM) ; Ethanol: 76mg/ml (199.26 mM)
Smiles
[Na+].COCCCOC1=C (C) C (CS (=O) C2=NC3=CC=CC=C3[N-]2) =NC=C1
Molecular Formula
C18H20N3NaO3S
Molecular Weight
381.42
Storage Conditions
Storage temperature: -20°C. Stability: ≥ 2 years
Notes
For research use only.
Other Product Names
Sodium;2-[[4- (3-methoxypropoxy) -3-methylpyridin-2-yl]methylsulfinyl]benzimidazol-1-ide
Available Sizes
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