IOWH-032
A novel and potent CFTR inhibitor (IC50=1.01 uM) in T84 and CHO-CFTR cell based assays for the treatment of cystic fibrosis; potentially serves as lead compound for development of new drugs for the treatment of cystic fibrosis. (In Vitro) :IOWH-032 (10 μM; 0-72 h) increases the ACE-2 expression in SARS-CoV-2 infected CFBE41o- WT cells.
Product Specifications
CAS Number
1191252-49-9
Product Name Alternative
IOWH-032 | IOWH032 | IOWH 032
Purity
>98% (HPLC)
Solubility
10 mM in DMSO
Smiles
O=C (C1=NC (C2=CC (Br) =C (O) C (Br) =C2) =NO1) NCC3=CC=C (OC4=CC=CC=C4) C=C3
Molecular Formula
C22H15Br2N3O4
Molecular Weight
545.1802
Storage Conditions
Storage temperature: -20°C. Stability: ≥ 2 years
Notes
For research use only.
Other Product Names
1,2,4-Oxadiazole-5-carboxamide, 3- (3,5-dibromo-4-hydroxyphenyl) -N-[ (4-phenoxyphenyl) methyl]-
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