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MW-150

MW-150 (MW01-18-150 SRM) is a novel potent, selective, CNS penetrant and orally active inhibitor of p38α MAPK with Ki of 101 nM; effectively suppresses hippocampal-dependent associative and spatial memory deficits in synaptic dysfunction mouse models; also can selectively modulate neuroinflammatory responses associated with pathology progression.

Product Specifications

CAS Number

1628502-91-9

Product Name Alternative

MW01-18-150SRM | MW 150 | MW150

Purity

>98% (HPLC)

Solubility

In Vitro: DMSO : 40 mg/mL (104.86 mM)

Smiles

CN1CCN (CC1) C2=NN=C (C (=C2) C3=CC=NC=C3) C4=CC5=CC=CC=C5C=C4

Molecular Formula

C24H23N5

Molecular Weight

381.483

Storage Conditions

Storage temperature: -20°C. Stability: ≥ 2 years

Notes

For research use only.

Other Product Names

6- (4-methylpiperazin-1-yl) -3- (naphthalen-2-yl) -4- (pyridin-4-yl) pyridazine

Available Sizes

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