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Compound 401

A synthetic inhibitor of DNA-PK also inhibits mTOR (IC50=5.3 uM) ; no inhibition on p110α/p85α PI3K (>100 uM) ; blocks the phosphorylation of S6 kinase 1 Thr389 and Akt Ser473 in COS7 cells.

Product Specifications

CAS Number

168425-64-7

Product Name Alternative

Compound-401 | Compound401

Field of Research

Pharmacology & Drug Discovery

Purity

>98% (HPLC)

Solubility

DMSO: 6 mg/mL

Smiles

O=C1C=C (N2CCOCC2) N=C3N1C=CC4=C3C=CC=C4

Molecular Formula

C16H15N3O2

Molecular Weight

281.3092

Storage Conditions

Storage temperature: -20°C. Stability: ≥ 2 years

Notes

For research use only.

Other Product Names

4H-Pyrimido[2,1-a]isoquinolin-4-one, 2- (4-morpholinyl) -

Available Sizes

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