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Sutezolid

An oxazolidinone antibiotic that possesses potent antituberculosis activity in vitro and in vivo; significantly shorten the duration of therapy for drug-susceptible as well as multidrug-resistant tuberculosis.Bacterial Infection Phase 2 Clinical (In Vitro) :Sutezolid (PNU-100480) exhibits excellent in vitro activity against multiple clinical isolates of Mycobacterium avium complex (MIC’s=0.5-4 μg/mL) . (In Vivo) :Sutezolid (PNU-100480) is a thiomorpholinyl analog of linezolid with superior efficacy against M. tuberculosis in the hollow-fiber, mouse, and whole-blood models.

Product Specifications

CAS Number

168828-58-8

Product Name Alternative

PNU-100480 | PNU100480 | PF-02341272 | PF02341272 | U-100480

Purity

>98% (HPLC)

Solubility

10 mM in DMSO

Smiles

CC (NC[C@H]1CN (C2=CC=C (N3CCSCC3) C (F) =C2) C (O1) =O) =O

Molecular Formula

C16H20FN3O3S

Molecular Weight

353.4117

Storage Conditions

Storage temperature: -20°C. Stability: ≥ 2 years

Notes

For research use only.

Other Product Names

Acetamide, N-[[ (5S) -3-[3-fluoro-4- (4-thiomorpholinyl) phenyl]-2-oxo-5-oxazolidinyl]methyl]-

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