CM 346
Afobazole (CM346) is an anxiolytic drug; produces anxiolytic and neuroprotective effects without any sedative or muscle relaxant actions. (In Vitro) :Afobazole's mechanism of action remains poorly defined however, with GABAergic, NGF and BDNF release promoting, MT1 receptor antagonism, MT3 receptor antagonism, and sigma agonism suggested as potential mechanisms. Afobazole was shown to inhibit MAO-A reversibly and there might be also some involvement with serotonin receptors. Afobazole has found little clinical use outside of Russia and has not been evaluated by the FDA.
Product Specifications
CAS Number
173352-21-1
Product Name Alternative
Obenoxazine
Purity
>98% (HPLC)
Solubility
Soluble in DMSO
Smiles
CCOC1=CC=C2C (N=C (SCCN3CCOCC3) N2) =C1
Molecular Formula
C15H21N3O2S
Molecular Weight
307.41
Storage Conditions
Storage temperature: -20°C. Stability: ≥ 2 years
Notes
For research use only.
Other Product Names
4- (2- ((5-ethoxy-1H-benzo[d]imidazol-2-yl) thio) ethyl) morpholine
Available Sizes
Frequently Asked Questions
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