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Tizoxanide

Tizoxanide is the main metabolite of nitazoxanide, which is a synthetic nitrothiazolyl-salicylamide derivative and an antiprotozoal agent.Parasite Infection Approved (In Vitro) :Tizoxanide (TIZ) induces mild mitochondrial uncoupling and activate AMPK in hepatocytes.Tizoxanide (TIZ) inhibits hepatitis C virus (HCV) replication in HCV replicon systems. (In Vivo) :Tizoxanide (TIZ) (10 mg/kg; i.v.) can pass the BBB and distribute to the brain tissue. Tizoxanide retains in brain is obviously longer than that in plasma.

Product Specifications

CAS Number

173903-47-4

Product Name Alternative

NSC697856 | Tizoxanide | Desacetylnitazoxanide | Desacetyl-nitazoxanide

Purity

>98% (HPLC)

Solubility

DMSO: ≥ 38 mg/mL

Smiles

O=C (NC1=NC=C ([N+] ([O-]) =O) S1) C2=CC=CC=C2O

Molecular Formula

C10H7N3O4S

Molecular Weight

265.2453

Storage Conditions

Storage temperature: -20°C. Stability: ≥ 2 years

Notes

For research use only.

Other Product Names

Benzamide, 2-hydroxy-N- (5-nitro-2-thiazolyl) -

Available Sizes

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