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AN-2690

An antifungal compound that inhibits cytoplasmic leucyl-tRNA synthetase for the potential treatment of nnychomycosis; inhibits T. rubrum, T. mentagrophytes, C. albicans, C. neoformans with MIC50s of 0.25-1ug/mL. (In Vitro) :Tavaborole (AN-2690) shows an 8-fold increase in activity against C. neoformans, and an 8-fold increase in activity against A. fumigatus. Tavaborole (AN-2690) obviously inhibit the cells expressing GlLeuRS-D444A, but has no effect on the cells expressing GlLeuRS and GlLeuRS-D444E.

Product Specifications

CAS Number

174671-46-6

Product Name Alternative

Tavaborole | AN2690 | AN 2690

Purity

>98% (HPLC)

Solubility

10 mM in DMSO

Smiles

OB1OCC2=CC (F) =CC=C12

Molecular Formula

C7H6BFO2

Molecular Weight

151.9307

Storage Conditions

Storage temperature: -20°C. Stability: ≥ 2 years

Notes

For research use only.

Other Product Names

2,1-Benzoxaborole, 5-fluoro-1,3-dihydro-1-hydroxy-

Available Sizes

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