AN-2690
An antifungal compound that inhibits cytoplasmic leucyl-tRNA synthetase for the potential treatment of nnychomycosis; inhibits T. rubrum, T. mentagrophytes, C. albicans, C. neoformans with MIC50s of 0.25-1ug/mL. (In Vitro) :Tavaborole (AN-2690) shows an 8-fold increase in activity against C. neoformans, and an 8-fold increase in activity against A. fumigatus. Tavaborole (AN-2690) obviously inhibit the cells expressing GlLeuRS-D444A, but has no effect on the cells expressing GlLeuRS and GlLeuRS-D444E.
Product Specifications
CAS Number
174671-46-6
Product Name Alternative
Tavaborole | AN2690 | AN 2690
Purity
>98% (HPLC)
Solubility
10 mM in DMSO
Smiles
OB1OCC2=CC (F) =CC=C12
Molecular Formula
C7H6BFO2
Molecular Weight
151.9307
Storage Conditions
Storage temperature: -20°C. Stability: ≥ 2 years
Notes
For research use only.
Other Product Names
2,1-Benzoxaborole, 5-fluoro-1,3-dihydro-1-hydroxy-
Available Sizes
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