NQDI-1
NQDI-1 is a potent and selective inhibitor of apoptosis signal-regulating kinase 1 (ASK1) with Ki of 500 nM; inhibits in vivo expression levels of ASK1, phosphorylated (p) JNK, p c Jun, p53 and caspase 3 in Hypoxia-ischemia rat model; enhances endochondral bone formation by increasing chondrocyte survival in mice.
Product Specifications
CAS Number
175026-96-7
Product Name Alternative
NQDI 1
Purity
>98% (HPLC)
Solubility
DMSO: 10 mg/mL
Smiles
O=C (C1=C2C3=C (NC1=O) C=CC=C3C (C4=C2C=CC=C4) =O) OCC
Molecular Formula
C19H13NO4
Molecular Weight
319.3108
Storage Conditions
Storage temperature: -20°C. Stability: ≥ 2 years
Notes
For research use only.
Other Product Names
3H-Naphtho[1,2,3-de]quinoline-1-carboxylic acid, 2,7-dihydro-2,7-dioxo-, ethyl ester
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