TAME hydrochloride
TAME is a small molecule anaphase-promoting complex/cyclosome (APC/C) inhibitor that binds to the APC preferentially suppresses APC/C (Cdc20) rather than APC/C (Cdh1) ; inhibits cyclin proteolysis in mitotic Xenopus egg extract with IC50 of 12 uM; promotes Cdc20 autoubiquitination, blocks cyclin degradation in interphase extract.
Product Specifications
CAS Number
1784-03-8
Product Name Alternative
Tosyl-L-arginine methyl ester hydrochloride
Purity
>98% (HPLC)
Solubility
DMSO: 37.9 mg/mL (100 mM) (< 1 mg/ml refers to the product slightly soluble or insoluble)
Smiles
N=C (N) NCCC[C@@H] (C (OC) =O) NS (=O) (C1=CC=C (C) C=C1) =O.[H]Cl
Molecular Formula
C14H22N4O4S.HCl
Molecular Weight
378.87
Storage Conditions
Storage temperature: -20°C. Stability: ≥ 2 years
Notes
For research use only.
Other Product Names
Arginine, N2- (p-tolylsulfonyl) -, methyl ester, monohydrochloride, L- (8CI)
Available Sizes
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