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TA-01

A potent inhibitor of Casein Kinase CK1ε, CK1δ and p38α with IC50 of 6.4, 6.8 and 6.7 nM, respectively; inhibits the phosphorylation of proteins downstream of p38α MAPK such as MAPKAPK2 and HSP27 during cardiogenesis, and increases ATF-2 and MEF2C during cardiac differentiation.

Product Specifications

CAS Number

1784751-18-3

Product Name Alternative

TA01 | TA 01

Purity

>98% (HPLC)

Solubility

10 mM in DMSO

Smiles

FC1=CC=CC=C1C2=C (C3=CC=NC=C3) NC (C4=C (F) C=CC=C4F) =N2

Molecular Formula

C20H12F3N3

Molecular Weight

351.3246

Storage Conditions

Storage temperature: -20°C. Stability: ≥ 2 years

Notes

For research use only.

Other Product Names

Pyridine, 4-[2- (2,6-difluorophenyl) -4- (4-fluorophenyl) -1H-imidazol-5-yl]-

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